Promoter type influences transcriptional topography by targeting genes to distinct nucleoplasmic sites
نویسندگان
چکیده
منابع مشابه
Promoter type influences transcriptional topography by targeting genes to distinct nucleoplasmic sites.
Both the sequence of a promoter and the position of a gene in 3D nuclear space play crucial roles in gene regulation, but few studies address their inter-relationship. Using human and viral promoters on mini-chromosomes and RNA fluorescence in situ hybridization coupled to 'high-precision' localization, we show that promoters binding the same transcription factors and responding to the same sig...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2013
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.123653